个人简介

副教授，硕士生导师，理学博士。2019年加入重庆医科大学基础医学院，主要从事¹⁸F放射性标记反应研究和纳米小分子前药递送系统的研究，主持国家自然科学基金项目1项，在学术期刊JACS，Org. Lett，Angew等发表学术文章10多篇。

教育背景及工作经历

2005-2009安庆师范大学材料化学专业学士

2009-2012厦门大学有机化学专业 硕士

2012-2015 中国科学院上海有机化学研究所博士

2016-2019中国科学院上海有机化学研究所 研究助理

2019-至今 重庆医科大学基础医学院放射医学教研室副教授

主持科研项目

2020年，国家自然科学基金青年项目，过渡金属催化¹⁸F-标记的少氟烷基化研究(22001028)

代表性论文、专利

1.Miao, W.; Zhao, Y.; Ni, C.; Gao, B.; Zhang, W.; Hu, J*. Iron-Catalyzed Difluoromethylation of Arylzincs with Difluoromethyl 2-Pyridyl Sulfone.J. Am. Chem. Soc.2018,140, 880–883.

2.Miao, W.; Ni, C.; Xiao, P.; Jia, R.; Zhang, W.; Hu, J*.Nickel-Catalyzed Reductive 2-Pyridination of Aryl Iodides with Difluoromethyl 2-Pyridyl Sulfone.Org. Lett.2021,23, 711–715.

3.Miao, W.; Ni, C.; Zhao, Y.; Hu, J*. Nucleophilic Iododifluoromethylation of Carbonyl Compounds Using Difluoromethyl 2-Pyridyl Sulfone.Org. Lett.2016,18, 2766–2769.

4.Miao, W.; Gao, Y.; Li, X.; Gao, Y.; Tang, G*.; Zhao, Y. Copper-Catalyzed Synthesis of Alkylphosphonates from H-Phosphonates and N-Tosylhydrazones.Adv. Synth. Catal.2012,354, 2659–2664.

5.Miao, W.; Ni, C.; Zhao, Y.; Hu, J*. Radical (2-pyridylsulfonyl)difluoromethylation of terminal alkenes with iododifluoromethyl 2-pyridyl sulfone.J. Fluorine Chem.2014,167, 231-236.

6. Wei, Z.;Miao, W.; Ni, C.; Hu, J*. Iron-Catalyzed Fluoroalkylation of Arylborates with Sulfone Reagents: Beyond the Limitation of Reduction Potential.Angew. Chem., Int. Ed.2021,60, 13597–13602.

7. Shen, X.;Miao, W.; Ni, C.; Hu, J*. Stereoselective Nucleophilic Fluoromethylation of Aryl Ketones: Dynamic Kinetic Resolution of Chiral α-Fluoro Carbanions.Angew. Chem., Int. Ed.2014,53, 775-779.

8. Zhu, J.;Miao, W.; Bao, L.; Ji, T.; Tang, G*.; Xu, P.; Zhao, Y. A Mild Method for the Cleavage of the 4-Picolyloxy Group with Magnesium under Neutral Conditions.Synlett2012,2012, 142-144.

9. Xiao, P.; Ni, C.;Miao, W.; Zhou, M.; Hu, J.; Chen, D.; Hu, J*. Fluoroalkylation of Various Nucleophiles with Fluoroalkyl Sulfones through a Single Electron Transfer Process.J. Org. Chem.2019,84, 8345-8359.

10. Hu, M.; Rong, J.;Miao, W.; Ni, C.; Han, Y.; Hu, J*. Copper-Mediated Trifluoromethylthiolation of α-Diazoesters.Org. Lett.2014,16, 2030-2033.