个人简介
陈显军,博士,副研究员,硕士生导师。2017年毕业于陆军军医大学,获博士学位。2015~2016年,赴美国Emory大学留学2年。2018~2019年,就职于联勤保障部队全军精神疾病防治研究所。2020年退役后入职重庆医科大学,并入选重庆医科大学基础医学院首届“优秀青年人才培育”计划。本人持续关注少突胶质细胞与抑郁症等重性精神疾病的关系,以第一作者、通讯作者在Glia, Translational Psychiatry, Neuroscience bulletin等杂志发表SCI论文10余篇。现主持国家自然科学基金1项,省部级科研项目1项。
教育背景及工作经历
2007-2011西南大学学士
2011-2017陆军军医大学博士
2020-2021 重庆医科大学助理研究员
2021-至今 重庆医科大学 副研究员
学术兼职
2020-至今中国神经科学学会会员、中国生理学会会员
主持科研项目
(1)国家自然科学基金委员会,青年科学基金项目, 32000684,精神分裂症易感基因FEZ1调控少突胶质细胞发育及其在精神行为中的作用机制, 2021-01-01至2023-12-31, 24万元,主持.
(2)重庆市科技局,博士直通车, CSTB2022BSXM-JCX0056, FEZ1调控少突胶质细胞形态重塑参与髓鞘再生的作用研究, 2022-09至2024-08, 10万元,主持
代表性论文、专利
1. Haoqian Wu#,Xianjun Chen#, Bin Yu, Jieqiong Zhang, Xingmei Gu, Wei Liu, Feng Mei*, Jian Ye*, Lan Xiao*. Deficient deposition of new myelin impairs adult optic nerve function in a murine model of diabetes, Glia, 2023, Jan 20.
2. Mei Li#, Lan Xiao*,Xianjun Chen*. Histone Acetylation and Methylation Underlie Oligodendroglial and Myelin Susceptibility in Schizophrenia, Frontiers in Cellular Neuroscience, 2022, 16 (823708).
3.Xianjun Chen#, Nan-Xin Huang, Yong-Jie Cheng, Qi-Yan Cai, Yan-Ping Tian, Xing-Shu Chen* and Lan Xiao*. DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice, Frontiers in Neuroscience, 2021, 15 (659853).
4.Xianjun Chen#, Hao Liu, Jingli Gan, Xiaorui Wang, Guangdan Yu, Tao Li, Xuejun Liang, Bin Yu and Lan Xiao*. Quetiapine Modulates Histone Methylation Status in Oligodendroglia and Rescues Adolescent Behavioral Alterations of Socially Isolated Mice, Frontiers in Psychiatry, 2020, 10 (984).
5.Xianjun Chen#, Fei Wang, Jingli Gan, Zhonghua Zhang, Xuejun Liang, Tao Li, Nanxin Huang, Xiaofeng Zhao, Feng Mei, Lan Xiao*. Myelin Deficits Caused by Olig2 Deficiency Lead to Cognitive Dysfunction and Increase Vulnerability to Social Withdrawal in Adult Mice,Neuroscience Bulletin, 2020, 36(4): 419–426.
6.Xianjun Chen#, Huifeng Duan, Lan Xiao and Jingli Gan*. Genetic and Epigenetic Alterations Underlie Oligodendroglia Susceptibility and White Matter Etiology in Psychiatric Disorders, Frontiers in Genetics, 2018, 9 (565).
7.Xianjun Chen#, Li Ku, Ruyi Mei, Guanglu Liu, Chongchong Xu, Zhexing Wen, Xiaofeng Zhao, Fei Wang, Lan Xiao* and Yue Feng*. Novel schizophrenia risk factor pathways regulate FEZ1 to advance oligodendroglia development, Translational Psychiatry, 2017, 7 (1293).
8.Xianjun Chen#,Weiguo Zhang,Tao Li,Yu Guo,Yanping Tian,Fei Wang,Shubao Liu,Hai-Ying Shen,Yue Feng*,Lan Xiao*. Impairment of Oligodendroglia Maturation Leads to Aberrantly Increased Cortical Glutamate and Anxiety-Like Behaviors in Juvenile Mice, Frontiers in Cellular Neuroscience, 2015, Dec 15;9:467.