个人简介

蒋宁，2019年获重庆医科大学博士学位；同年入职重庆医科大学基础医学院病理学教研室，2021年任副教授，2022年被评为硕士生导师（病理学与病理生理学方向）。主要从事病理学教学、临床病理诊断和肝胆胰肿瘤病理研究。主持国家自然科学基金及重庆市自然科学基金3项。获得专利5项，第一作者或通讯作者在领域国际权威刊物上发表SCI论文20余篇，单篇影响因子最高19.92，累计影响因子大于150。担任多个国外杂志通讯审稿专家。

教育背景及工作经历

2008.9-2013.6，重庆医科大学，临床医学，学士

2013.9-2016.6，重庆医科大学，临床医学，硕士

2016.9-2019.6，重庆医科大学，基础医学，博士

2019.9-2021.11，医师&讲师，重庆医科大学病理科

2021.12-至今，副教授，重庆医科大学病理科

学术兼职

中国微循环学会转化医学委员会青年会员

重庆市生物信息学会肿瘤信息学专业委员会委员

奖项及荣誉

重庆医科大学2023年教学创新大赛校级“三等奖”

2021-2023学年连续教评“优秀”

主持科研项目

1. 国家自然科学基金委员会，青年科学基金项目，30万元，在研，主持

2. 重庆市自然科学基金面上，10万元，在研，主持

3. 重庆市教委科技项目，4万元，在研，主持

4. 重庆医科大学, 未来医学青年创新团队项目, 2021-01-01至2023-12-31, 50万元, 在研, 主持

5. 重庆医科大学基础医学院, 2023年“优秀青年人才”项目, 10万元, 在研, 主持

6. 重庆医科大学基础医学院, 首批“优秀青年人才”项目, 10万元, 结题, 主持

7. 国家自然科学基金委员会，面上项目，55万元，在研，参与

8. 国家自然科学基金委员会，青年科学基金项目，21万元，结题，参与

9. 国家自然科学基金委员会，面上项目，54万元，结题，参与

10. 国家自然科学基金委员会，青年科学基金项目，20万元，结题，参与

代表性论文、专利

1. Liu S#, Xiao X#, Zhang L#, Wang J#, Zhao W, Liu H, Liao R, Li Z, Xu M, Guo J, Zhou B*, Du C*, Peng Q*, Jiang N*. Reprogramming Exosomes to Escape from Immune Surveillance for Mitochondrial Protection in Hepatic Ischemia-Reperfusion Injury. Theranostics 2024; 14(1):116-132.（co-corresponding author，IF：12.4）

2. Zhang L#, Zhang X, Liu H, Yang C, Yu J, Zhao W, Guo J, Zhou B*, Jiang N*. MTFR2-dependent mitochondrial fission promotes HCC progression. J Transl Med. 2024 Jan 18;22(1):73.（co-corresponding author，IF：7.4）

3. Luo J#, Luo Y#, Chen J#, Gao Y, Tan J, Yang Y, Yang C, Jiang N*, Luo Y*. Intestinal metabolite UroB alleviates cerebral ischemia/reperfusion injury by promoting competition between TRIM65 and TXNIP for binding to NLRP3 inflammasome in response to neuroinflammation. Biochim Biophys Acta Mol Basis Dis. 2024 Feb 13;1870(4):167056. （co-corresponding author，IF：6.2）

4. Liu H#, Li Z#, Zhang L, Zhang M, Liu S, Wang J, Yang C, Peng Q, Du C*, Jiang N*. Necroptosis-Related Prognostic Model for Pancreatic Carcinoma Reveals Its Invasion and Metastasis Potential through Hybrid EMT and Immune Escape. Biomedicines. 2023 Jun 16;11(6):1738.（co-corresponding author，IF：4.7）

5. Zhang X#, Li L#, Zhang M, Zhang L, Liu S, Guo J, Jiang N*, Peng Q*, Wang J*, Ding S. Intelligent recognition of CTCs from gallbladder cancer by ultrasensitive electrochemical cytosensor and diagnosis of chemotherapeutic resistance. Biosens Bioelectron. 2023 May 15;228:115183. doi: 10.1016/j.bios.2023.115183. Epub 2023 Feb 27. PMID: 36905863.（co-corresponding author，IF：12.55）

6. Xinyu Xiao#, Yu Gao#, Shanshan Liu#, Meijiao Wang, Min Zhong, Jianwei Wang*, Ning Jiang*, Qiling Peng*.A “nano-courier” for Precise Delivery of Acetylcholine and Melatonin by C5a-targeted Aptamers Effectively Attenuates Reperfusion Injury of Ischemic Stroke[J]. Advanced Functional Materials, 2023.（co-corresponding author，IF：19.92）

7. Liu L#, Xiao X, Guo J, Wang J, Liu S, Wang M*, Peng Q*, Jiang N*. Aptamer and Peptide-Engineered Polydopamine Nanospheres for Target Delivery and Tumor Perfusion in Synergistic Chemo-Phototherapy of Pancreatic Cancer. ACS Appl Mater Interfaces. 2023 Apr 5;15(13):16539-16551.（co-corresponding author，IF：10.38）

8. Wang J#, Wang M#, Jiang N*, et al. Emerging chemical engineering of exosomes as" bioscaffolds" in diagnostics and therapeutics[J]. Genes & Diseases, 2022.（co-corresponding author，IF：7.243）

9. Gao Y#, Xiao X#, Luo J, Wang J, Peng Q, Zhao J, Jiang N*, Zhao Y*. E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury. Int J Mol Sci. 2022 Nov 7;23(21):13648.（co-corresponding author，IF：6.208）

10. Zhang L#, Zhang X, Zhao W, Xiao X, Liu S, Peng Q, Jiang N*, Zhou B*. NLRP6-Dependent Pyroptosis-Related lncRNAs Predict the Prognosis of Hepatocellular Carcinoma. Front Med (Lausanne). 2022 Mar 2;9:760722. doi: 10.3389/fmed.2022.760722. PMID: 35308537; PMCID: PMC8924451.(co-corresponding author，IF：5.06)

11. Mi Zhang#, Xinyu Xiao, Liang Liu, Shanshan Liu, Haichuan Liu, Taojian Fan, Bin Zhang, Swelm Wageh, Ahmed Al-Ghamdi, Meijiao Wang, Jianwei Wang, Chengyou Du*, Ning Jiang*, Han Zhang, Qiling Peng*. Aptamer‐Conjugated Biocompatible Nanospheres for Fluorescent Imaging–Guided Hepatocellular Carcinoma–Targeted Phototherapeutic Modality[J]. Advanced NanoBiomed Research, 2022, 2(9): 2200014.(co-corresponding author)

12. Zhang M#, Zhao W, Liu S, Liu H, Liu L, Peng Q, Du C*, Jiang N*. H/ACA snoRNP Gene Family as Diagnostic and Prognostic Biomarkers for Hepatocellular Carcinoma. Pharmgenomics Pers Med. 2021 Oct 19;14:1331-1345. doi: 10.2147/PGPM.S333838. PMID: 34703278; PMCID: PMC8541795.(co-corresponding author，IF：3.912)

13. Liu S#, Zhao W, Li X, Zhang L, Gao Y, Peng Q, Du C*, Jiang N*. AGTRAP Is a Prognostic Biomarker Correlated With Immune Infiltration in Hepatocellular Carcinoma. Front Oncol. 2021 Sep 14;11:713017. doi: 10.3389/fonc.2021.713017. PMID: 34595113; PMCID: PMC8477650.(co-corresponding author，IF：6.244)

14. Luo J#, Chen J, Yang C, Tan J, Zhao J, Jiang N*, Zhao Y*. 6-Gingerol protects against cerebral ischemia/reperfusion injury by inhibiting NLRP3 inflammasome and apoptosis via TRPV1 / FAF1 complex dissociation-mediated autophagy. Int Immunopharmacol. 2021 Nov;100:108146. doi: 10.1016/j.intimp.2021.108146. Epub 2021 Sep 17. Erratum in: Int Immunopharmacol. 2023 Aug;121:110411. PMID: 34537481. (co-corresponding author，IF：5.71)

15. Yang C#, Chen J, Yu Z, Luo J, Li X, Zhou B*, Jiang N*. Mining of RNA Methylation-Related Genes and Elucidation of Their Molecular Biology in Gallbladder Carcinoma. Front Oncol. 2021 Feb 25;11:621806. doi: 10.3389/fonc.2021.621806. PMID: 33718182; PMCID: PMC7947712. (co-corresponding author，IF：6.244)

16. Zhou B#, Yang C, Yan X, Shi Z, Xiao H, Wei X, Jiang N*, Wu Z*. LETM1 Knockdown Promotes Autophagy and Apoptosis Through AMP-Activated Protein Kinase Phosphorylation-Mediated Beclin-1/Bcl-2 Complex Dissociation in Hepatocellular Carcinoma. Front Oncol. 2021 Jan 21;10:606790. doi: 10.3389/fonc.2020.606790. PMID: 33552978; PMCID: PMC7859436.(co-corresponding author，IF：6.244)

17. Zhou B#, Zhao W#, Feng R#, Zhang X, Li X, Zhou Y, Peng L, Li Y, Zhang J, Luo J, Li L, Wu J, Yang C, Wang M, Zhao Y, Wang K, Yu H, Peng Q, Jiang N*. The pathological autopsy of coronavirus disease 2019 (COVID-2019) in China: a review. Pathog Dis. 2020 Apr 1;78(3):ftaa026. doi: 10.1093/femspd/ftaa026. PMID: 32533838; PMCID: PMC7314003. (Corresponding author，IF：3.166)

18. Zhang X#, Zhang X, Li X, Ma J, Xie D, Jiang N*. Dishevelled-1 regulated apoptosis through NF-κB in cerebral ischemia/reperfusion injury in rats. Neurosci Lett. 2020 Mar 23;722:134862. doi: 10.1016/j.neulet.2020.134862. Epub 2020 Feb 24. PMID: 32105766. (Corresponding author，IF：3.046)

19. Zhang J#, Jiang N#, Zhang L, Meng C, Zhao J, Wu J. NLRP6 expressed in astrocytes aggravates neurons injury after OGD/R through activating the inflammasome and inducing pyroptosis. Int Immunopharmacol. 2020 Mar;80:106183. doi: 10.1016/j.intimp.2019.106183. Epub 2020 Jan 9. PMID: 31927506. (Co-first author，IF：4.932)

20. Ning J#, Junyi T, Chang M, Yueting W, Jingyan Z, Jin Z, Jing Z, Yong Z. TOM7 silencing exacerbates focal cerebral ischemia injury in rat by targeting PINK1/Beclin1-mediated autophagy. Behav Brain Res. 2019 Mar 15;360:113-119. doi: 10.1016/j.bbr.2018.11.031. Epub 2018 Nov 20. PMID: 30468788.(First author，IF：2.977)

21. Liao R#, Jiang N#, Tang ZW#, Li de W, Huang P, Luo SQ, Gong JP, Du CY. Systemic and intratumoral balances between monocytes/macrophages and lymphocytes predict prognosis in hepatocellular carcinoma patients after surgery. Oncotarget. 2016 May 24;7(21):30951-61. doi: 10.18632/oncotarget.9049. PMID: 27129159; PMCID: PMC5058730.(Co-first author，IF：5.168)

22. Xiao H#, Jiang N#, Zhou B, Liu Q, Du C. TAZ regulates cell proliferation and epithelial-mesenchymal transition of human hepatocellular carcinoma. Cancer Sci. 2015 Feb;106(2):151-9. doi: 10.1111/cas.12587. Epub 2015 Jan 30. PMID: 25495189; PMCID: PMC4399022.(Co-first author，IF：3.9）

23. 蒋宁，周宝勇，廖锐，等. MYH9 在肝癌中的表达及其对 SMMC-7721 增殖和凋亡 的影响[J]. 基础医学与临床,2016,(07):912-917.

24. 蒋宁, 唐涛, 胡凌波, 等. 肝移植术后乙型肝炎复发的防治[J]. 中华器官移植杂志. 2015, 36(006): 378-381.

25. 专利：一项荧光成像装置。（专利号：202220103038.1）彭奇龄，张密，蒋宁，王建为。

26. 专利：AV3 肽功能化的聚多巴胺纳米递送系统靶向 CD71 蛋白及其制备方法。（专利号：202211318717.1）刘亮，蒋宁，彭奇龄，王建为。

27. 专利：一项胰腺癌药物制备用搅拌装置。（专利号：202222606949.9）刘亮，蒋宁，彭奇龄，王建为。

28. 专利：特异性检测胆囊癌CTCs超灵敏电化学免疫传感器的制备及应用方法。（申请号：202211460426.6）王建为，张秀珍，李露，彭奇龄，蒋宁。