个人简介

副教授，硕士生导师，理学博士。2019年加入重庆医科大学基础医学院，主要从事¹⁸F放射性标记反应研究和纳米小分子前药递送系统的研究，主持国家自然科学基金项目1项，在学术期刊JACS，Org. Lett，Angew等发表学术文章10多篇。

教育背景及工作经历

2005-2009 安庆师范大学材料化学专业 学士

2009-2012 厦门大学有机化学专业  硕士

2012-2015  中国科学院上海有机化学研究所 博士

2016-2019 中国科学院上海有机化学研究所  研究助理

2019-至今   重庆医科大学基础医学院放射医学教研室 副教授

主持科研项目

2020年，国家自然科学基金青年项目，过渡金属催化¹⁸F-标记的少氟烷基化研究(22001028)

代表性论文、专利

1. Miao, W.; Zhao, Y.; Ni, C.; Gao, B.; Zhang, W.; Hu, J*. Iron-Catalyzed Difluoromethylation of Arylzincs with Difluoromethyl 2-Pyridyl Sulfone. J. Am. Chem. Soc. 2018, 140, 880–883.

2. Miao, W.; Ni, C.; Xiao, P.; Jia, R.; Zhang, W.; Hu, J*. Nickel-Catalyzed Reductive 2-Pyridination of Aryl Iodides with Difluoromethyl 2-Pyridyl Sulfone. Org. Lett. 2021, 23, 711–715.

3. Miao, W.; Ni, C.; Zhao, Y.; Hu, J*. Nucleophilic Iododifluoromethylation of Carbonyl Compounds Using Difluoromethyl 2-Pyridyl Sulfone. Org. Lett. 2016, 18, 2766–2769.

4. Miao, W.; Gao, Y.; Li, X.; Gao, Y.; Tang, G*.; Zhao, Y. Copper-Catalyzed Synthesis of Alkylphosphonates from H-Phosphonates and N-Tosylhydrazones. Adv. Synth. Catal. 2012, 354, 2659–2664.

5. Miao, W.; Ni, C.; Zhao, Y.; Hu, J*. Radical (2-pyridylsulfonyl)difluoromethylation of terminal alkenes with iododifluoromethyl 2-pyridyl sulfone. J. Fluorine Chem. 2014, 167, 231-236.

6. Wei, Z.; Miao, W.; Ni, C.; Hu, J*. Iron-Catalyzed Fluoroalkylation of Arylborates with Sulfone Reagents: Beyond the Limitation of Reduction Potential. Angew. Chem., Int. Ed. 2021, 60, 13597–13602.

7. Shen, X.; Miao, W.; Ni, C.; Hu, J*. Stereoselective Nucleophilic Fluoromethylation of Aryl Ketones: Dynamic Kinetic Resolution of Chiral α-Fluoro Carbanions. Angew. Chem., Int. Ed. 2014, 53, 775-779.

8. Zhu, J.; Miao, W.; Bao, L.; Ji, T.; Tang, G*.; Xu, P.; Zhao, Y. A Mild Method for the Cleavage of the 4-Picolyloxy Group with Magnesium under Neutral Conditions. Synlett 2012, 2012, 142-144.

9. Xiao, P.; Ni, C.; Miao, W.; Zhou, M.; Hu, J.; Chen, D.; Hu, J*. Fluoroalkylation of Various Nucleophiles with Fluoroalkyl Sulfones through a Single Electron Transfer Process. J. Org. Chem. 2019, 84, 8345-8359.

10. Hu, M.; Rong, J.; Miao, W.; Ni, C.; Han, Y.; Hu, J*. Copper-Mediated Trifluoromethylthiolation of α-Diazoesters. Org. Lett. 2014, 16, 2030-2033.