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肖倩
副研究员,硕士生导师
招生专业:放射医学
研究方向:抑郁症发病与治疗的神经生物学机制
通讯地址:重庆市渝中区医学院路1号重庆医科大学生命科学院B07号房间
电子邮箱(电话):xiaoqian@cqmu.edu.cn;023-68485060

个人简介

副研究员、硕士生导师、医学博士。2018年加入重庆医科大学,在基础医学院博士后流动站做师资博士后。主持国家自然科学基金项目1项,省部级科研项目1项。在国内外学术刊物发表学术文章50余篇。

教育背景及工作经历

2006-2011 南华大学临床医学专业 学士

2011-2014 重庆医科大学人体解剖与组织胚胎学专业 硕士

2014-2018  重庆医科大学临床检验诊断学专业 博士

2018-2020  重庆医科大学基础医学院博士后流动站 博士后

2020至今 重庆医科大学基础医学院放射医学教研室 副研究员

主持科研项目

2021年,国家自然科学基金青年科学基金项目,跑步锻炼通过作用海马内大麻素型受体促进神经元新生的抗抑郁机制研究(82001435

2020年,重庆市科学技术局博士后面上项目,跑步锻炼通过激活CB1R/ERK/CREB信号通路促进神经元再生的抗抑郁机制研究(cstc2020jcyj-bshX0098

代表性论文、专利

1. Xiao Q#, Luo Y#, Lv F, He Q, Wu H, Chao F, Qiu X, Zhang L, Gao Y, Huang C, Wang S, Zhou C, Zhang Y, Jiang L, Tang Y. Protective Effects of 17β-Estradiol on Hippocampal Myelinated Fibers in Ovariectomized Middle-aged Rats. Neuroscience. 2018 Aug 10; 385:143-153.

2. Xiao Q, Wang F, Luo Y, Chen L, Chao F, Tan C, Gao Y, Huang C, Zhang L, Liang X, Tang J, Qi Y, Jiang L, Zhang Y, Zhou C, Tang Y. Exercise protects myelinated fibers of white matter in a rat model of depression. J Comp Neurol. 2018 Feb 15;526(3):537-549.

3. Luo Y, Xiao Q, Wang J, Jiang L, Hu M, Jiang Y, Tang J, Liang X, Qi Y, Dou X, Zhang Y, Huang C, Chen L, Tang Y. Running exercise protects oligodendrocytes in the medial prefrontal cortex in chronic unpredictable stress rat model. Transl Psychiatry. 2019 Nov 28;9(1):322.

4. Luo Y, Xiao Q, Chao F, He Q, Lv F, Zhang L, Gao Y, Qiu X, Huang C, Li Y, Wang S, Jiang R, Gu H, Tang Y. 17β-estradiol replacement therapy protects myelin sheaths in the white matter of middle-aged female ovariectomized rats: a stereological study. Neurobiol Aging. 2016 Nov;47:139-148.

5. Huang CX, Xiao Q, Zhang L, Gao Y, Ma J, Liang X, Tang J, Wang SR, Luo YM, Chao FL, Xiu Y, Tang Y. Stress-induced myelin damage in the hippocampal formation in a rat model of depression. J Psychiatr Res. 2022 Nov;155:401-409.

6. Huang CX#, Zhang L#, Xiao Q, Li C, Qiu X, Chao FL, Xiu Y, Wang SR, Zhang Y, Tang Y. Effects of 4-month running exercise on the spatial learning ability and white matter volume and microvessels of middle-aged female and male rats. J Comp Neurol. 2022 Oct;530(15):2749-2761.

7. He Q, Luo Y, Lv F, Xiao Q, Chao F, Qiu X, Zhang L, Gao Y, Xiu Y, Huang C, Tang Y. Effects of estrogen replacement therapy on the myelin sheath ultrastructure of myelinated fibers in the white matter of middle-aged ovariectomized rats. J Comp Neurol. 2018 Apr 1; 526(5):790-802.

8. Xiao K, Luo Y, Liang X, Tang J, Wang J, Xiao Q, Qi Y, Li Y, Zhu P, Yang H, Xie Y, Wu H, Tang Y. Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats. Transl Psychiatry. 2021 Sep 6;11(1):461.

9. Zhang SS, Zhu L, Peng Y, Zhang L, Chao FL, Jiang L, Xiao Q, Liang X, Tang J, Yang H, He Q, Guo YJ, Zhou CN, Tang Y. Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice. J Neuroinflammation. 2022 Feb 5;19(1):34.

10. Liu L, Tang J, Liang X, Li Y, Zhu P, Zhou M, Qin L, Deng Y, Li J, Wang Y, Jiang L, Huang D, Zhou Y, Wang S, Xiao Q, Luo Y, Tang Y. Running exercise alleviates hippocampal neuroinflammation and shifts the balance of microglial M1/M2 polarization through adiponectin/AdipoR1 pathway activation in mice exposed to chronic unpredictable stress. Mol Psychiatry. 2024 Feb 15.