个人简介
陈显军,博士,副研究员,硕士生导师。2017年毕业于陆军军医大学,获博士学位。2015~2016年,赴美国 Emory 大学留学 2 年。2018~2019年,就职于联勤保障部队全军精神疾病防治研究所。2020 年退役后入职重庆医科大学,并入选重庆医科大学基础医学院首届“优秀青年人才培育”计划。本人持续关注少突胶质细胞与抑郁症等重性精神疾病的关系, 以第一作者、通讯作者在 Glia, Translational Psychiatry, Neuroscience bulletin 等杂志发表 SCI 论文10余篇。现主持国家自然科学基金 1 项,省部级科研项目1 项。
教育背景及工作经历
2007-2011 西南大学 学士
2011-2017 陆军军医大学 博士
2020-2021 重庆医科大学 助理研究员
2021-至今 重庆医科大学 副研究员
学术兼职
2020-至今 中国神经科学学会会员、中国生理学会会员
主持科研项目
(1)国家自然科学基金委员会, 青年科学基金项目, 32000684, 精神分裂症易感基因FEZ1调控少突胶质细 胞发育及其在精神行为中的作用机制, 2021-01-01 至 2023-12-31, 24万元, 主持.
(2)重庆市科技局, 博士直通车, CSTB2022BSXM-JCX0056, FEZ1调控少突胶质细胞形态重塑参与髓鞘再生 的作用研究, 2022-09 至 2024-08, 10万元, 主持
代表性论文、专利
1. Haoqian Wu#, Xianjun Chen#, Bin Yu, Jieqiong Zhang, Xingmei Gu, Wei Liu, Feng Mei*, Jian Ye*, Lan Xiao*. Deficient deposition of new myelin impairs adult optic nerve function in a murine model of diabetes, Glia, 2023, Jan 20.
2. Mei Li#, Lan Xiao*, Xianjun Chen*. Histone Acetylation and Methylation Underlie Oligodendroglial and Myelin Susceptibility in Schizophrenia, Frontiers in Cellular Neuroscience, 2022, 16 (823708).
3. Xianjun Chen#, Nan-Xin Huang, Yong-Jie Cheng, Qi-Yan Cai, Yan-Ping Tian, Xing-Shu Chen* and Lan Xiao*. DNA Hypermethylation Induced by L-Methionine Leads to Oligodendroglial and Myelin Deficits and Schizophrenia-Like Behaviors in Adolescent Mice, Frontiers in Neuroscience, 2021, 15 (659853).
4. Xianjun Chen#, Hao Liu, Jingli Gan, Xiaorui Wang, Guangdan Yu, Tao Li, Xuejun Liang, Bin Yu and Lan Xiao*. Quetiapine Modulates Histone Methylation Status in Oligodendroglia and Rescues Adolescent Behavioral Alterations of Socially Isolated Mice, Frontiers in Psychiatry, 2020, 10 (984).
5. Xianjun Chen#, Fei Wang, Jingli Gan, Zhonghua Zhang, Xuejun Liang, Tao Li, Nanxin Huang, Xiaofeng Zhao, Feng Mei, Lan Xiao*. Myelin Deficits Caused by Olig2 Deficiency Lead to Cognitive Dysfunction and Increase Vulnerability to Social Withdrawal in Adult Mice,Neuroscience Bulletin, 2020, 36(4): 419–426.
6. Xianjun Chen#, Huifeng Duan, Lan Xiao and Jingli Gan*. Genetic and Epigenetic Alterations Underlie Oligodendroglia Susceptibility and White Matter Etiology in Psychiatric Disorders, Frontiers in Genetics, 2018, 9 (565).
7. Xianjun Chen#, Li Ku, Ruyi Mei, Guanglu Liu, Chongchong Xu, Zhexing Wen, Xiaofeng Zhao, Fei Wang, Lan Xiao* and Yue Feng*. Novel schizophrenia risk factor pathways regulate FEZ1 to advance oligodendroglia development, Translational Psychiatry, 2017, 7 (1293).
8. Xianjun Chen#, Weiguo Zhang, Tao Li, Yu Guo, Yanping Tian, Fei Wang, Shubao Liu, Hai-Ying Shen, Yue Feng*, Lan Xiao*. Impairment of Oligodendroglia Maturation Leads to Aberrantly Increased Cortical Glutamate and Anxiety-Like Behaviors in Juvenile Mice, Frontiers in Cellular Neuroscience, 2015, Dec 15;9:467.