个人简介
二级教授、博士生导师、医学博士、特聘教授。曾连任两届国际体视学会副主席和中国体视学会副理事长，现任中国体视学会常务理事和生物体视学分会副主任委员，重庆市解剖学会、神经科学学会副理事长。系全国先进工作者，中国侨联首批特聘专家，曾以第一完成人获重庆市自然科学一等奖。先后承担及参与课题30项（主持9 项国家自然科学基金项目）；发表论著230多篇（SCI收录论文130多篇，被SCI 论文引用4000 余次）；先后30余次在国际性学术会议上报告研究成果，包括新闻发布会上发布研究成果、特邀报告和大会主题发言；招收和培养博士、硕士研究生和博士后百余名。
教育背景及工作经历
1979-1983 四川医科大学（原泸州医学院）医学专业 学士
1983-1987 川北医学院解剖教研室 助教
1987-1990 四川大学 (原华西医科大学)人体解剖与组织胚胎学专业 硕士
1990-1994 川北医学院解剖教研室 讲师
1992-1994 川北医学院科研处 副处长
1994-1995 丹麦Aarhus 大学体视学研究室 访问学者
1995-1998 丹麦Aarhus 大学医学专业 博士
1998-1999 美国Northwestern 大学细胞和分子生物学系 博士后
1999-2000 美国UCLA神经研究中心 博士后研究员
2001 美国UCLA神经研究中心 助理研究员
2001-2004 美国纽约大学Mount Sinai Medical Center神经生物学系 博士后研究员
2004-至今 重庆医科大学组织胚胎教研室 教授
2005-2006 重庆医科大学基础医学院 副院长
2006-至今 重庆医科大学神经病学专业、人体解剖与组织胚胎学专业 博士生导师
2006 重庆医科大学科研处 副处长
2007-2008 重庆医科大学基础医学研究所 副所长
2008-2022 重庆医科大学基础医学院 副院长
2020-至今 重庆医科大学 特聘教授
学术兼职
2008-2015 国际体视学会副主席
2010-2017 中国体视学会副理事长
2017-至今 中国体视学会理事长顾问
2017-至今 中国体视学会常务理事
2009-至今 中国生物体视学会副主任委员
2014-至今 全国生物医学体视学首席科学传播专家
2014-至今 重庆市解剖学会副理事长
2019-至今 重庆市神经科学学会副理事长
2010-2015 中国科学技术协会决策咨询专家库成员
2009-至今 SCI杂志《Image Analysis & Stereology》编委
2013-至今 《中国体视学与图像分析》编委会副主任委员
2010-至今 《解剖学报》、《中国组织化学与细胞化学杂志》、《解剖学研究》等杂志编委
2010-至今 《重庆医科大学学报》编委
奖项及荣誉
2015年，全国先进工作者
2015年，重庆医科大学年度人物
2015年，重庆医科大学优秀研究生导师
2014年，第五届中国侨界贡献奖（创新人才）
2013年，国务院颁发政府特殊津贴及证书
2012年，重庆市首批百名学术学科领军人才
2011年，重庆医科大学重大科技成果奖
2011年，重庆医科大学优秀研究生导师
2011年，重庆医科大学优秀创新团队奖
2010年，TAU 蛋白病异常神经网络新靶点研究，重庆市自然科学一等奖（第一完成人）
2010年，中国侨联首届特聘专家
2010年，重庆市基础医学创新团队带头人
2009年，全国归侨侨眷先进个人
2009年，中国体视学会工作突出贡献奖
2008年，重庆市第二届学术技术带头人
2006年，重庆市‘322’工程第一层次人选
主持科研项目
2022年，国家自然科学基金面上项目，跑步锻炼通过脂联素、鸢尾素介导海马内多靶点抗抑郁的机制研究（82171522）
2019年，国家自然科学基金面上项目，跑步锻炼通过多靶点缩短经典抗抑郁药物起效潜伏期的机制研究（81871073）
2017年，国家自然科学基金面上项目，氟西汀通过5-HT系统多靶点对抗AD病理过程的作用和机制（81671259）
2015年，国家自然科学基金面上项目，跑步锻炼对转基因痴呆小鼠海马改变作用的研究（81470057）
2013年，国家自然科学基金面上项目，跑步锻炼对老年大脑白质毛细血管的作用及机制研究（31271288）
2012年，国家自然科学基金面上项目，丰富生存环境对大脑海马老年改变作用的研究（81171238）
2012年，重庆市首批“百名学术学科领军人才”培养计划
2010年，国家自然科学基金面上项目，跑步训练对大脑白质神经纤维老年改变作用的研究（30973155）
2010年，重庆高校创新团队建设计划（201010）
2009年，重庆市自然科学基金重点项目，老年性痴呆早期病理机制的探讨及其锻炼对其影响的研究（CSTC，2009BA5035）
2008年，教育部2008年度高等学校博士学科点专项科研项目，老年性痴呆早期大脑白质有髓神经纤维改变及锻炼对其影响的研究（200806310007）
2008年，重庆医科大学2008年度校级课题重点项目，老年性痴呆早期白质病理改变的机制及其防治的研究（XBZD200801）
2007年，重庆市教委科学技术研究项目，延缓大脑衰老进程靶结构的探索（KJ070319）
2006年，国家自然科学基金面上项目，白质神经纤维老年改变的机制及丰富的生存环境对其影响的研究（30572075）
2006年，教育部重点项目，延缓大脑衰老进程的靶结构的探讨（206124）
2006年，教育部留学回国人员科研启动基金，大脑衰老的机制研究
2005年，国家自然科学基金主任基金，锻炼和丰富的生存环境延缓脑衰老的机制研究（30440082）
2005年，国家人事部2005年度高层次留学人才回国工作资助项目，大脑衰老的机制及延缓大脑衰老进程的手段的研究（2005年重庆市唯一获资助者）
2005年，重庆市自然科学基金，大脑白质神经纤维老年改变的机制研究（CSTC, 2005BB5034）
代表性论文
1. Liu L, Tang J, Liang X, Li Y, Zhu P, Zhou M, Qin L, Deng Y, Li J, Wang Y, Jiang L, Huang D, Zhou Y, Wang S, Xiao Q, Luo Y*, Tang Y*. Running exercise alleviates hippocampal neuroinflammation and shifts the balance of microglial M1/M2 polarization through adiponectin/AdipoR1 pathway activation in mice exposed to chronic unpredictable stress. Mol Psychiatry. 2024 Feb 15. doi: 10.1038/s41380-024-02464-1. Online ahead of print.
2. Xie YH#, Jiang L#, Zhang Y, Deng YH, Yang H, He Q, Zhou YN, Zhou CN, Luo YM, Liang X, Wang J, Huang DJ, Zhu L, Tang Y*, Chao FL*. Antagonizing LINGO-1 reduces activated microglia and alleviates dendritic spine loss in the hippocampus of APP/PS1 transgenic mice. Neurosci Lett. 2024 Jan 18;820:137612. doi: 10.1016/j.neulet.2023.137612. Epub 2023 Dec 22.
3. Qin L, Liang X, Qi Y, Luo Y, Xiao Q, Huang D, Zhou C, Jiang L, Zhou M, Zhou Y, Tang J*, Tang Y*.
MPFC PV+ interneurons are involved in the antidepressant effects of running exercise but not fluoxetine therapy. Neuropharmacology. 2023 Nov 1;238:109669. doi: 10.1016/j.neuropharm.2023.109669. Epub 2023 Jul 19.
4. Liu M, Zhu L, Guo YJ, Zhang SS, Jiang L, Zhang Y, Chao FL*, Tang Y*. The effects of voluntary running exercise on the astrocytes of the medial prefrontal cortex in APP/PS1 mice. J Comp Neurol. 2023 Aug;531(11):1147-1162. doi: 10.1002/cne.25485. Epub 2023 May 5.
5. Zhou YN, Jiang L, Zhang Y, Zhou CN, Yang H, He Q, Wang YY, Xiao Q, Huang DJ, Luo YM, Tang Y*, Chao FL*. Anti-LINGO-1 antibody protects neurons and synapses in the medial prefrontal cortex of APP/PS1 transgenic mice. Neurosci Res. 2023 Aug;193:28-40. doi: 10.1016/j.neures.2023.02.005. Epub 2023 Feb 17.
6. Zhang M, Kong X, Chen J, Liu W, Liu C, Dou X, Jiang L, Luo Y, Song M, Miao P, Tang Y*, Xiu Y*. Dysfunction of GluN3A subunit is involved in depression-like behaviors through synaptic deficits. J Affect Disord. 2023 Jul 1;332:72-82. doi: 10.1016/j.jad.2023.03.076. Epub 2023 Mar 28.
7. Zhao H#, Zhang T#, Zhao F, Tan M, Du S, Wang Y, Li J, Du J, Tang Y, Zhao Y*. Changes in myelinated fibers in the hippocampus of streptozotocin-induced diabetic rats: a stereological investigation. Folia Morphol (Warsz). 2023 Jun 7. doi: 10.5603/FM.a2023.0040. Online ahead of print.
8. Wang YY, Zhou YN, Jiang L, Wang S, Zhu L, Zhang SS, Yang H, He Q, Liu L, Xie YH, Liang X, Tang J, Chao FL*, Tang Y*. Long-term voluntary exercise inhibited AGE/RAGE and microglial activation and reduced the loss of dendritic spines in the hippocampi of APP/PS1 transgenic mice. Exp Neurol. 2023 May;363:114371. doi: 10.1016/j.expneurol.2023.114371. Epub 2023 Mar 4.
9. Zhang X, Sun D, Zhou X, Zhang C, Yin Q, Chen L, Tang Y, Liu Y*, Morozova-Roche LA*. Proinflammatory S100A9 stimulates TLR4/NF-kappaB signaling pathways causing enhanced phagocytic capacity of microglial cells. Immunol Lett. 2023 Mar;255:54-61. doi: 10.1016/j.imlet.2023.02.008. Epub 2023 Mar 3.
10. Wang C, Zou Q, Pu Y, Cai Z*, Tang Y*. Berberine Rescues D-Ribose-Induced Alzheimer's Pathology via Promoting Mitophagy. Int J Mol Sci. 2023 Mar 20;24(6):5896. doi: 10.3390/ijms24065896.
11. Zang Q, Wang S, Qi Y, Zhang L, Huang C, Xiu Y, Zhou C, Luo Y, Jia G, Li S, Zhang Y*, Tang Y*. Running exercise improves spatial learning and memory ability and enhances angiogenesis in the cerebral cortex via endogenous nitric oxide. Behav Brain Res. 2023 Feb 15;439:114243. doi: 10.1016/j.bbr.2022.114243. Epub 2022 Dec 1.
12. Huang D, Xiao Q, Tang J, Liang X, Wang J, Hu M, Jiang Y, Liu L, Qin L, Zhou M, Li Y, Zhu P, Deng Y, Li J, Zhou C, Luo Y*, Tang Y*. Positive effects of running exercise on astrocytes in the medial prefrontal cortex in an animal model of depression. J Comp Neurol. 2022 Dec;530(17):3056-3071. doi: 10.1002/cne.25397. Epub 2022 Aug 16.
13. Huang CX, Xiao Q, Zhang L, Gao Y, Ma J, Liang X, Tang J, Wang SR, Luo YM, Chao FL, Xiu Y, Tang Y*. Stress-induced myelin damage in the hippocampal formation in a rat model of depression. J Psychiatr Res. 2022 Nov;155:401-409. doi: 10.1016/j.jpsychires.2022.09.025. Epub 2022 Sep 21.
14. Li J, Zhu P, Li Y, Xiao K, Tang J, Liang X, Luo Y, Wang J, Deng Y, Jiang L, Xiao Q, Guo Y, Tang Y, Huang C*. The liver X receptors agonist GW3965 attenuates depressive-like behaviors and suppresses microglial activation and neuroinflammation in hippocampal subregions in a mouse depression model. J Comp Neurol. 2022 Nov;530(16):2852-2867. doi: 10.1002/cne.25380. Epub 2022 Jun 27.
15. Tian Y, Cao R, Che B, Sun D, Tang Y, Jiang L, Bai Q, Liu Y*, Morozova-Roche LA*, Zhang C*. Proinflammatory S100A9 Regulates Differentiation and Aggregation of Neural Stem Cells. ACS Chem Neurosci. 2020 Nov 4;11(21):3549-3556. doi: 10.1021/acschemneuro.0c00365. Epub 2020 Oct 20.
16. Chen J, Luo Y, Liang X, Kong X, Xiao Q, Tang J, Qi Y, Tang Y*, Xiu Y*. Alteration in NMDAR subunits in different brain regions of chronic unpredictable mild stress (CUMS) rat model. Transl Neurosci. 2022 Oct 26;13(1):379-389. doi: 10.1515/tnsci-2022-0255. eCollection 2022 Jan 1.
17. Huang CX, Zhang L, Xiao Q, Li C, Qiu X, Chao FL, Xiu Y, Wang SR, Zhang Y, Tang Y*. Effects of 4-month running exercise on the spatial learning ability and white matter volume and microvessels of middle-aged female and male rats. J Comp Neurol. 2022 Oct;530(15):2749-2761. doi: 10.1002/cne.25354. Epub 2022 Jun 8.
18. Cheng N, Xiong Y, Zhang W, Wu X, Sun Z, Zhang L, Wu H, Tang Y*, Peng Y*. Astrocytes promote the proliferation of oligodendrocyte precursor cells through connexin 47-mediated LAMB2 secretion in exosomes. Mol Biol Rep. 2022 Aug;49(8):7263-7273. doi: 10.1007/s11033-022-07508-9. Epub 2022 May 20.
19. Liang X, Tang J, Qi YQ, Luo YM, Yang CM, Dou XY, Jiang L, Xiao Q, Zhang L, Chao FL, Zhou CN, Tang Y*. Exercise more efficiently regulates the maturation of newborn neurons and synaptic plasticity than fluoxetine in a CUS-induced depression mouse model. Exp Neurol. 2022 Aug;354:114103. doi: 10.1016/j.expneurol.2022.114103. Epub 2022 May 5.
20. Zhu P, Tang J, Liang X, Luo Y, Wang J, Li Y, Xiao K, Li J, Deng Y, Jiang L, Xiao Q, Qi Y, Xie Y, Yang H, Zhu L, Tang Y, Huang C*. Activation of liver X receptors protects oligodendrocytes in CA3 of stress-induced mice. Front Pharmacol. 2022 Jul 25;13:936045. doi: 10.3389/fphar.2022.936045. eCollection 2022.
21. Yang H, Jiang L, Zhang Y, Liang X, Tang J, He Q, Luo YM, Zhou CN, Zhu L, Zhang SS, Xiao K, Zhu PL, Wang J, Li Y, Chao FL*, Tang Y*. Anti-LINGO-1 antibody treatment alleviates cognitive deficits and promotes maturation of oligodendrocytes in the hippocampus of APP/PS1 mice. J Comp Neurol. 2022 Jul;530(10):1606-1621. doi: 10.1002/cne.25299. Epub 2022 Jan 27.
22. Yang Z, Zhang W, Liu D, Zhang SS, Tang Y, Song J, Long J, Yang J, Jiang H, Li Y, Liu X, Lü Y*, Ding F*. Effects of sport stacking on neuropsychological, neurobiological, and brain function performances in patients with mild Alzheimer's disease and mild cognitive impairment: a randomized controlled trial. Front Aging Neurosci. 2022 May 12;14:910261. doi: 10.3389/fnagi.2022.910261. eCollection 2022.
23. Zhu L#, Fan JH#, Chao FL, Zhou CN, Jiang L, Zhang Y, Luo YM, Zhang L, Xiao Q, Yang H, Zhang SS, Wu H, Tang Y*. Running exercise protects spinophilin-immunoreactive puncta and neurons in the medial prefrontal cortex of APP/PS1 transgenic mice. J Comp Neurol. 2022 Apr;530(6):858-870. doi: 10.1002/cne.25252. Epub 2021 Oct 20.
24. Zhang SS, Zhu L, Peng Y, Zhang L, Chao FL, Jiang L, Xiao Q, Liang X, Tang J, Yang H, He Q, Guo YJ, Zhou CN*, Tang Y*. Long-term running exercise improves cognitive function and promotes microglial glucose metabolism and morphological plasticity in the hippocampus of APP/PS1 mice. J Neuroinflammation. 2022 Feb 5;19(1):34. doi: 10.1186/s12974-022-02401-5.
25. Tang J, Liang X, Dou X, Qi Y, Yang C, Luo Y, Chao F, Zhang L, Xiao Q, Jiang L, Zhou C, Tang Y*. Exercise rather than fluoxetine promotes oligodendrocyte differentiation and myelination in the hippocampus in a male mouse model of depression. Transl Psychiatry. 2021 Dec 8;11(1):622. doi: 10.1038/s41398-021-01747-3.
26. Xiao K, Luo Y, Liang X, Tang J, Wang J, Xiao Q, Qi Y, Li Y, Zhu P, Yang H, Xie Y, Wu H*, Tang Y*. Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats. Transl Psychiatry. 2021 Sep 6;11(1):461. doi: 10.1038/s41398-021-01571-9.
27. He Q, Jiang L, Zhang Y, Yang H, Zhou CN, Xie YH, Luo YM, Zhang SS, Zhu L, Guo YJ, Deng YH, Liang X, Xiao Q, Zhang L, Tang J, Huang DJ, Zhou YN, Dou XY, Chao FL*, Tang Y*. Anti-LINGO-1 antibody ameliorates cognitive impairment, promotes adult hippocampal neurogenesis, and increases the abundance of CB1R-rich CCK-GABAergic interneurons in AD mice. Neurobiol Dis. 2021 Aug;156:105406. doi: 10.1016/j.nbd.2021.105406. Epub 2021 May 24.
28. Jing F, Zou Q, Wang Y, Cai Z*, Tang Y*. Activation of microglial GLP-1R in the trigeminal nucleus caudalis suppresses central sensitization of chronic migraine after recurrent nitroglycerin stimulation.
29. J Headache Pain. 2021 Jul 29;22(1):86. doi: 10.1186/s10194-021-01302-x.
30. Zhang Y*, Chao FL, Zhou CN, Jiang L, Zhang L, Liang X, Tang J, Tang Y. Atrophy of lacunosum moleculare layer is important for learning and memory in APP/PS1 transgenic mice. Neuroreport. 2021 May 5;32(7):596-602. doi: 10.1097/WNR.0000000000001639.
31. Zhao Y*, Liu J, Li J, Zhao F, Du S, Wang Y, Li J, Yang L, Du J, Tang Y. Changes in hippocampal capillaries in transgenic type 2 diabetic mice: A stereological investigation.Anat Rec (Hoboken). 2021 May;304(5):1071-1083. doi: 10.1002/ar.24525. Epub 2020 Nov 16.
32. Xie YH, Zhou CN, Liang X, Tang J, Yang CM, Luo YM, Chao FL, Jiang L, Wang J, Qi YQ, Zhu PL, Li Y, Xiao K, Tang Y*. Anti-Lingo-1 antibody ameliorates spatial memory and synapse loss induced by chronic stress. J Comp Neurol. 2021 May 1;529(7):1571-1583. doi: 10.1002/cne.25038. Epub 2020 Sep 30.
33. Wang J, Tang J, Liang X, Luo Y, Zhu P, Li Y, Xiao K, Jiang L, Yang H, Xie Y, Zhang L, Deng Y, Li J, Tang Y*. Hippocampal PGC-1α-mediated positive effects on parvalbumin interneurons are required for the antidepressant effects of running exercise. Transl Psychiatry. 2021 Apr 15;11(1):222. doi: 10.1038/s41398-021-01339-1.
34. Li Y, Luo Y, Tang J, Liang X, Wang J, Xiao Q, Zhu P, Xiao K, Jiang L, Dou X, Huang C, Xie Y, Tang Y*. The positive effects of running exercise on hippocampal astrocytes in a rat model of depression. Transl Psychiatry. 2021 Feb 1;11(1):83. doi: 10.1038/s41398-021-01216-x.
35. Chao FL, Zhang Y, Zhang L, Jiang L, Zhou CN, Tang J, Liang X, Fan JH, Dou XY, Tang Y*. Fluoxetine promotes hippocampal oligodendrocyte maturation and delays learning and memory decline in APP/PS1 mice. Front Aging Neurosci. 2021 Jan 13;12:627362. doi: 10.3389/fnagi.2020.627362. eCollection 2020.
36. Gou DH, Huang TT, Li W, Gao XD, Haikal C, Wang XH, Song DY, Liang X, Zhu L, Tang Y, Ding C, Li JY*. Inhibition of copper transporter 1 prevents α-synuclein pathology and alleviates nigrostriatal degeneration in AAV-based mouse model of Parkinson's disease. Redox Biol. 2021 Jan;38:101795. doi: 10.1016/j.redox.2020.101795. Epub 2020 Nov 12.
37. Chen L#, Chao FL#, Lu W, Zhang L, Huang CX, Yang S, Qiu X, Yang H, Zhao YY, Wang SR, Li C*, Tang Y*. Long-Term Running Exercise Delays Age-Related Changes in White Matter in Rats.Front Aging Neurosci. 2020 Oct 23;12:590530. doi: 10.3389/fnagi.2020.590530. eCollection 2020.
38. Wang J, Luo Y, Tang J, Liang X, Huang C, Gao Y, Qi Y, Yang C, Chao F, Zhang Y, Tang Y*.The effects of fluoxetine on oligodendrocytes in the hippocampus of chronic unpredictable stress-induced depressed model rats.J Comp Neurol. 2020 Oct 15;528(15):2583-2594. doi: 10.1002/cne.24914. Epub 2020 Apr 11.
39. Qi Y, Wang S, Luo Y, Huang W, Chen L, Zhang Y, Liang X, Tang J, Zhang Y, Zhang L, Chao F, Gao Y, Zhu Y, Tang Y*. Exercise-induced nitric oxide contributes to spatial memory and hippocampal capillaries in rats. Int J Sports Med. 2020 Oct;41(13):951-961. doi: 10.1055/a-1195-2737. Epub 2020 Jul 8.
40. Yang C, Tang J, Liang X, Qi Y, Luo Y, Xie Y, Wang J, Jiang L, Zhou C, Huang C, Tang Y*. Anti-LINGO-1 antibody treatment improves chronic stress-induced spatial memory impairments and oligodendrocyte loss in the hippocampus. Behav Brain Res. 2020 Sep 1;393:112765. doi: 10.1016/j.bbr.2020.112765. Epub 2020 Jun 11.
41. Zhang W, Zhang X, Zhang L, Xu D, Cheng N, Tang Y, Peng Y*. Astrocytes increase exosomal secretion of oligodendrocyte precursor cells to promote their proliferation via integrin β4-mediated cell adhesion. Biochem Biophys Res Commun. 2020 May 28;526(2):341-348. doi: 10.1016/j.bbrc.2020.03.092. Epub 2020 Mar 24.
42. Zhang L, Tang W, Chao FL, Zhou CN, Jiang L, Zhang Y, Liang X, Tang J, Qi YQ, Yang H, He Q, Zhang SS, Zhu L, Peng Y*, Tang Y*. Four-month treadmill exercise prevents the decline in spatial learning and memory abilities and the loss of spinophilin-immunoreactive puncta in the hippocampus of APP/PS1 transgenic mice. Neurobiol Dis. 2020 Mar;136:104723. doi: 10.1016/j.nbd.2019.104723. Epub 2019 Dec 27.
43. Qiao P, Ma J, Wang Y, Huang Z, Zou Q, Cai Z*, Tang Y*. Curcumin prevents neuroinflammation by inducing microglia to transform into the M2-phenotype via CaMKKβ-dependent activation of the AMP-activated protein kinase signal pathway. Curr Alzheimer Res. 2020;17(8):735-752. doi: 10.2174/1567205017666201111120919.
44. Ma J, Gao Y, Tang W, Huang W, Tang Y*. Fluoxetine protects against dendritic spine loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice. Curr Alzheimer Res. 2020;17(1):93-103. doi: 10.2174/1567205017666200213095419.
45. Luo Y, Xiao Q, Wang J, Jiang L, Hu M, Jiang Y, Tang J, Liang X, Qi Y, Dou X, Zhang Y, Huang C, Chen L, Tang Y*. Running exercise protects oligodendrocytes in the medial prefrontal cortex in chronic unpredictable stress rat model. Transl Psychiatry. 2019 Nov 28;9(1):322. doi: 10.1038/s41398-019-0662-8.
46. Liang X, Tang J, Chao FL, Zhang Y, Chen LM, Wang FF, Tan CX, Luo YM, Xiao Q, Zhang L, Qi YQ, Jiang L, Huang CX, Gao Y, Tang Y*. Exercise improves depressive symptoms by increasing the number of excitatory synapses in the hippocampus of CUS-Induced depression model rats. Behav Brain Res. 2019 Nov 18;374:112115. doi: 10.1016/j.bbr.2019.112115. Epub 2019 Jul 29.
47. Tang J, Liang X, Zhang Y, Chen L, Wang F, Tan C, Luo Y, Xiao Q, Chao F, Zhang L, Gao Y, Huang C, Qi Y, Tang Y*. The effects of running exercise on oligodendrocytes in the hippocampus of rats with depression induced by chronic unpredictable stress. Brain Res Bull. 2019 Jul;149:1-10. doi: 10.1016/j.brainresbull.2019.04.001. Epub 2019 Apr 4.
48. Zhou CN, Chao FL, Zhang Y, Jiang L, Zhang L, Fan JH, Wu YX, Dou XY, Tang Y*. Fluoxetine delays the cognitive function decline and synaptic changes in a transgenic mouse model of early Alzheimer's disease. J Comp Neurol. 2019 Jun 1;527(8):1378-1387. doi: 10.1002/cne.24616. Epub 2019 Jan 25.
49. Zhang Y, Chao FL, Zhang L, Jiang L, Zhou CN, Chen LM, Lu W, Jiang R, Tang Y*. Quantitative study of the capillaries within the white matter of the Tg2576 mouse model of Alzheimer's disease. Brain Behav. 2019 Apr;9(4):e01268. doi: 10.1002/brb3.1268. Epub 2019 Mar 21.
50. Jiang L, Xu D, Zhang WJ, Tang Y*, Peng Y*.Astrocytes induce proliferation of oligodendrocyte progenitor cells via connexin 47-mediated activation of Chi3l1 expression. Eur Rev Med Pharmacol Sci. 2019 Apr;23(7):3012-3020.
51. Gao Y, Yao Y, Liang X, Tang J, Ma J, Qi YQ, Huang CX, Zhang Y, Chen LM, Chao FL, Zhang L, Luo YM, Xiao Q, Du L, Xiao Q, Wang SR, Tang Y*. Changes in white matter and the effects of fluoxetine on such changes in the CUS rat model of depression. Neurosci Lett. 2019 Feb 16;694:104-110. doi: 10.1016/j.neulet.2018.11.013. Epub 2018 Nov 10.
52. Zhou CN, Chao FL, Zhang Y, Jiang L, Zhang L, Luo YM, Xiao Q, Chen LM, Tang Y*. Sex differences in the white matter and myelinated fibers of APP/PS1 mice and the effects of running exercise on the sex differences of AD mice. Front Aging Neurosci. 2018 Aug 17;10:243. doi: 10.3389/fnagi.2018.00243. eCollection 2018.
53. Xiao Q#, Luo Y#, Lv F, He Q, Wu H, Chao F, Qiu X, Zhang L, Gao Y, Huang C, Wang S, Zhou C, Zhang Y, Jiang L, Tang Y*. Protective effects of 17β-estradiol on hippocampal myelinated fibers in ovariectomized middle-aged rats. Neuroscience. 2018 Aug 10;385:143-153. doi: 10.1016/j.neuroscience.2018.06.006. Epub 2018 Jun 14.
54. Jiang L, Ma J, Zhang Y, Zhou CN, Zhang L, Chao FL, Chen LM, Jiang R, Wu H, Tang Y*. Effect of running exercise on the number of the neurons in the hippocampus of young transgenic APP/PS1 mice. Brain Res. 2018 1692:56-65. doi: 10.1016/j.brainres.2018.04.033. Epub 2018 Apr 30.
55. Chao FL, Zhang L, Zhang Y, Zhou CN, Jiang L, Xiao Q, Luo YM, Lv FL, He Q, Tang Y*. Running exercise protects against myelin breakdown in the absence of neurogenesis in the hippocampus of AD mice. Brain Res. 2018 Apr 1;1684:50-59. doi: 10.1016/j.brainres.2018.01.007. Epub 2018 Jan 6.
56. He Q, Luo Y, Lv F, Xiao Q, Chao F, Qiu X, Zhang L, Gao Y, Xiu Y, Huang C, Tang Y*. Effects of estrogen replacement therapy on the myelin sheath ultrastructure of myelinated fibers in the white matter of middle-aged ovariectomized rats. J Comp Neurol. 2018 Apr 1;526(5):790-802. doi: 10.1002/cne.24366. Epub 2017 Dec 17.
57. Du L, Liu H, Du W, Chao F, Zhang L, Wang K, Huang C, Gao Y, Tang Y*. Stimulated left DLPFC-nucleus accumbens functional connectivity predicts the anti-depression and anti-anxiety effects of rTMS for depression. Transl Psychiatry. 2018 Mar 9;7(11):3. doi: 10.1038/s41398-017-0005-6.
58. Xiao Q, Wang F, Luo Y, Chen L, Chao F, Tan C, Gao Y, Huang C, Zhang L, Liang X, Tang J, Qi Y, Jiang L, Zhang Y, Zhou C, Tang Y*. Exercise protects myelinated fibers of white matter in a rat model of depression. J Comp Neurol. 2018 Feb 15;526(3):537-549. doi: 10.1002/cne.24350. Epub 2017 Nov 26.
59. Chao FL, Jiang L, Zhang Y, Zhou CN, Zhang L, Tang J, Liang X, Qi YQ, Zhu YQ, Ma J, Tang Y*. Stereological investigation of the effects of treadmill running exercise on the hippocampal neurons in middle-aged APP/PS1 transgenic mice, J Alzheimers Dis. 2018;63(2):689-703. doi: 10.3233/JAD-171017.
60. Chen L#, Zhou C#, Tan C, Wang F, Gao Y, Huang C, Zhang Y, Jiang L, Tang Y*. Stereological Study on the Positive Effect of Running Exercise on the Capillaries in the Hippocampus in a Depression Model. Front Neuroanat. 2017, 11: 93. doi: 10.3389/fnana.2017.00093. eCollection 2017.
61. Zhang Y, Chao FL, Zhou CN, Jiang L, Zhang L, Chen LM, Luo YM, Xiao Q, Tang Y*. Effects of exercise on capillaries in the white matter of transgenic AD mice. Oncotarget. 2017 Jul 22;8(39):65860-65875. doi: 10.18632/oncotarget.19505.
62. Xiu Y#, Cheng GH#, Peng C, Wang Y, Li YD, Chao FL, Tang Y*. Ultrastructural abnormalities and loss of myelinated fibers in the corpus callosum of demyelinated mice induced by cuprizone. J Neurosci Res. 2017 Aug;95(8):1677-1689. doi: 10.1002/jnr.23997. Epub 2016 Dec 9.
63. Gao Y#, Ma J#, Tang J, Liang X, Huang CX, Wang SR, Chen LM, Wang FF, Tan CX, Chao FL, Zhang L, Qiu X, Luo YM, Xiao Q, Tang Y*. White matter atrophy and myelinated fiber disruption in a rat model of depression. J Comp Neurol.2017;525(8):1922-1933. doi: 10.1002/cne.24178. Epub 2017 Mar 10.
64. Ma J, Gao Y, Jiang L, Chao FL, Huang W, Zhou C, Tang W, Zhang L, Huang C, Zhang Y, Luo Y, Xiao Q, Yu H, Jiang R, Tang Y*. Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer’s disease mice. Oncotarget. 2017 Apr 25;8(17):27676-27692. doi: 10.18632/oncotarget.15398.
65. Liu Z, Xu D, Wang S, Chen Y, Li Z, Gao X, Jiang L, Tang Y*, Peng Y*. Astrocytes induce proliferation of oligodendrocyte progenitor cells via connexin 47-mediated activation of the ERK/Id4 pathway. Cell Cycle. 2017:1-9. doi: 10.1080/15384101.2017.1295183. Epub 2017 Feb 22.
66. Zhang L, Chao FL, Luo YM, Xiao Q, Jiang L, Zhou CN, Zhang Y, Lv FL, He Q, Ma J, Tang Y*. Exercise prevents cognitive function decline and demyelination in the white matter of APP/PS1 transgenic AD mice. Curr Alzheimer Res. 2017;14(6):645-655. doi: 10.2174/1567205014666161213121353.
67. Li C#, Zhang L#, Chao F, Xiao Q, Luo Y, Tang Y*. Stereological quantification of age-related changes in myelinated fibers of rat white matter. Neuroreport. 2017 Jan 1;28(1):42-49.
68. Wang S, Qi Y, Yu L, Zhang L, Chao F, Huang W, Huang R, Li H, Luo Y, Xiu Y, Tang Y*. Endogenous nitric oxide regulates blood vessel growth factors, capillaries in the cortex, and memory retention in Sprague-Dawley rats. Am J Transl Res. 2016 Dec 15;8(12):5271-5285. eCollection 2016.
69. Chen LM#, Zhang AP#, Wang FF, Tan CX, Gao Y, Huang CX, Zhang Y, Jiang L, Zhou CN, Chao FL, Zhang L, Tang Y*. Running exercise protects the capillaries in the white matter in a rat model of depression. J Comp Neurol. 2016 Dec 1;524(17):3577-3586. doi: 10.1002/cne.24017. Epub 2016 May 3.
70. Luo Y, Xiao Q, Chao F, He Q, Lv F, Zhang L, Gao Y, Qiu X, Huang C, Li Y, Wang S, Jiang R, Gu H, Tang Y*.17β-estradiol replacement therapy protects myelin sheaths in the white matter of middle-aged female ovariectomized rats: a stereological study. Neurobiol Aging. 2016 Aug 8;47:139-148. doi: 10.1016/j.neurobiolaging.2016.07.023. Epub 2016 Aug 8.
71. Zhao F, Li J, Mo L, Tan M, Zhang T, Tang Y*, Zhao Y*.Changes in Neurons and Synapses in Hippocampus of Streptozotocin-Induced Type 1 Diabetes Rats: A Stereological Investigation.Anat Rec (Hoboken). 2016 Sep;299(9):1174-83. doi: 10.1002/ar.23344. Epub 2016 Apr 28.
72. Du L, Qiu H, Liu H, Zhao W, Tang Y, Fu Y, Li X, Qiu T, Hu H, Meng H, Luo Q. Changes in problem-solving capacity and association with spontaneous brain activity after a single electroconvulsive treatment in major depressive disorder. J ECT. 2016 Mar;32(1):49-54. doi: 10.1097/YCT.0000000000000269.
73. Lu W#, Yang S#, Zhang L, Chen L, Chao FL, Luo YM, Xiao Q, Gu HW, Jiang R, Tang Y*. Decreased myelinated fibers in the hippocampal dentate gyrus of the Tg2576 mouse model of Alzheimer's disease. Curr Alzheimer Res. 2016;13(9):1040-7. doi: 10.2174/1567205013666160314150709.
74. Yang S, Lu W, Zhou DS*, Tang Y*. Enriched environment increases myelinated fiber volume and length in brain white matter of 18-month female rats. Neurosci Lett. 2015 Apr 23;593:66-71. doi: 10.1016/j.neulet.2015.03.025. Epub 2015 Mar 18.
75. Wang S, Chen L, Zhang L, Huang C, Xiu Y, Wang F, Zhou C, Luo Y, Xiao Q, Tang Y*. Effects of long-term exercise on spatial learning, memory ability, and cortical capillaries in aged rats. Med Sci Monit. 2015 Apr 1;21:945-54. doi: 10.12659/MSM.893935.
76. Xiu Y, Kong XR, Zhang L, Qiu X, Gao Y, Huang CX, Chao FL, Wang SR, Tang Y*. The myelinated fiber loss in the corpus callosum of mouse model of schizophrenia induced by MK-801. J Psychiatr Res. 2015 Apr;63:132-40. doi: 10.1016/j.jpsychires.2015.02.013. Epub 2015 Feb 25.
77. Chao F, Zhang L, Luo Y, Xiao Q, Lv F, He Q, Zhou C, Zhang Y, Jiang L, Jiang R, Gu H, Tang Y*. Running exercise reduces myelinated fiber loss in the dentate gyrus of the hippocampus in APP/PS1 transgenic mice. Current Alzheimer Research, 12(4):377-383, 2015. Curr Alzheimer Res. 2015;12(4):377-83. doi: 10.2174/1567205012666150325183011.
78. Yang S, Lu W, Zhou DS, Tang Y*. Four-month enriched environment prevents myelinated fiber loss in the white matter during normal aging of male rats. Brain Struct Funct. 2015;220(3):1263-72. doi: 10.1007/s00429-014-0721-0. Epub 2014 Feb 20.
79. Xiu Y, Kong XR, Zhang L, Qiu X, Chao FL, Peng C, Gao Y, Huang CX, Wang SR, Tang Y*. White Matter Injuries Induced by MK-801 in a Mouse Model of Schizophrenia Based on NMDA Antagonism.Anat Rec (Hoboken), 297(8):1498-1507, 2014. Anat Rec (Hoboken). 2014 Aug;297(8):1498-507. doi: 10.1002/ar.22942. Epub 2014 May 2.
80. Pan Y, Yu L, Lei W, Guo Y, Wang J, Yu H, Tang Y, Yang J*. Beraprost sodium protects against chronic brain injury in aluminum-overload rats. Behav Brain Funct. 2015 Feb 7;11(1):6. doi: 10.1186/s12993-014-0051-7.
81. Lu W, Yang S, Chen L, Qiu X, Huang CX, Wu H, Li C, Yang JQ, Zhang L, Chao FL, Tang Y*. Stereological investigation of the age-related changes of the myelinated fibers in the hippocampus of male rats. Anat Rec (Hoboken). 2014 Aug;297(8):1490-7. doi: 10.1002/ar.22936. Epub 2014 Apr 30.
82. Zhao YY, Shi XY, Zhang L, Wu H, Chao FL, Huang CX, Gao Y, Qiu X, Chen L, Lu W, Tang Y*. Enriched environment induces higher CNPase positive cells in aged rat hippocampus. Neurosci Lett. 2013 Oct 25;555:177-81. doi: 10.1016/j.neulet.2013.09.032. Epub 2013 Sep 26.
83. Zhang L, Lu W, Chen L, Qiu X, Li C, Huang CX, Gong X, Min QC, Lu F, Wan JY, Chao FL, Tang Y*. The early changes in behavior and the myelinated fibers of the white matter in the Tg2576 transgenic mouse model of Alzheimer’s disease. Neurosci Lett. 2013 Oct 25;555:112-7. doi: 10.1016/j.neulet.2013.09.030. Epub 2013 Sep 20.
84. Yang S, Li C, Qiu X, Zhang L, Lu W, Chen L, Zhao YY, Shi XY, Huang CX, Cheng GH, Tang Y*. Effects of an enriched environment on myelin sheaths in white matter of rat during normal aging: A stereological study. Neuroscience. 2013 Mar 27;234:13-21. doi: 10.1016/j.neuroscience.2013.01.003. Epub 2013 Jan 10.
85. Huang CX, Qiu X, Wang SL, Wu H, Xia L, Li C, Gao Y, Zhang L, Xiu Y, Chao FL, Tang Y*. Exercise-induced changes of the capillaries in the cortex of middle-aged rats. Neuroscience. 2013 Mar 13;233:139-45. doi: 10.1016/j.neuroscience.2012.12.046. Epub 2013 Jan 3.
86. Zhao YY, Shi XY, Qiu X, Lu W, Yang S, Li C, Chen L, Zhang L, Cheng GH, Tang Y*. Enriched environment increases the myelinated nerve fibers of aged rat corpus callosum. Anat Rec (Hoboken). 2012 Jun;295(6):999-1005. doi: 10.1002/ar.22446. Epub 2012 Mar 19.
87. Yang S, Lu W, Zhou DS, Tang Y*. Enriched environment and white matter in aging brain. Anat Rec (Hoboken). 2012 Sep;295(9):1406-14. doi: 10.1002/ar.22526. Epub 2012 Jul 7.
88. Wang H, Jiang R, He Q, Zhang Y, Zhang Y, Li Y, Zhuang R, Luo Y, Li Y, Wan J, Tang Y, Yu H, Jiang Q, Yang J*. Expression pattern of peroxisome proliferator-activated receptors in rat hippocampus following cerebral ischemia and reperfusion injury.PPAR Res. 2012;2012:596394. doi: 10.1155/2012/596394. Epub 2012 Dec 9.
89. Ma XT, Tang Y, Lv Y, Cheng OM, Yan Y*. A quantitative study on changes of the myelinated fibers in the cerebral cortex of cortical dysplasia rats. Neural Regen Res. 2012 Feb 5;7(4):268-72. doi: 10.3969/j.issn.1673-5374.2012.04.005.
90. Qiu X, Huang CX, Lu W, Yang S, Li C, Shi XY, Chen L, Xiu Y, Yang JQ, Tang Y*. Effects of a 4 month enriched environment on the hippocampus and the myelinated fibers in the hippocampus of middle-aged rats. Brain Res. 2012 Jul 17:1465:26-33. doi: 10.1016/j.brainres.2012.05.025. Epub 2012 May 22.
91. Ma LY, Zhang DM, Tang Y, Lu Y, Zhang Y, Gao Y, Xia L, Zhao KX, Chai LY, Xiao Q*. Ghrelin-attenuated cognitive dysfunction in streptozotocin-induced diabetic rats. Alzheimer Dis Assoc Disord. 2011 Oct-Dec;25(4):352-63. doi: 10.1097/WAD.0b013e31820ce536.
92. Zhao YY, Shi XY, Qiu X, Zhang L, Lu W, Yang S, Li C, Cheng GH, Yang ZW, Tang Y*. Enriched environment increases the total number of CNPase positive cells in the corpus callosum of middle-aged rats. Acta Neurobiol Exp (Wars). 2011;71(3):322-30. doi: 10.55782/ane-2011-1854.
93. Chen L, Lu W, Yang Z, Yang S, Li C, Shi X, Tang Y*. Age-related changes of the oligodendrocytes in rat subcortical white matter. Anat Rec (Hoboken). 2011 Mar;294(3):487-93. doi: 10.1002/ar.21332. Epub 2011 Jan 31.
94. Qiu X, Li C, Jiang R, Chen L, Huang CX, Yang S, Lu W, Shi XY, Zhao YY, Gao Y, Cheng GH, Tang Y*. The effects of short-term enriched environment on capillaries of the middle-aged rat cortex. Neurosci Lett. 2011;505(2):186-190.
95. Xu Q, Lu W, Qiu X, Yang S, Li C, Zhang W, Tang Y*. Age related changes in the myelinated fibers of corpus callosum.Neurosci Lett. 2011;499(3):208-212.
96. Zhang L, Lu W, Yang S, Chen L, Qiu X, Chen GH, Tang Y*. Stereological methods for objectively quantifying myelin sheaths in the rat hippocampus. Neural Regen Res. 2011;6(31):2405-2409.
97. Shi XY, Zhao YY, Yang S, Li C, Lu W, Tang Y*. Side differences of the age-related changes in the white matter and the myelinated nerve fibers in the white matter of female rats. Neurosci Lett. 2011;492:119-123.
98. Shao WH, Li C, Chen L, Qiu X, Zhang W, Huang CX, Xia L, Kong JM, Tang Y*. Stereological investigation of age-related changes of the capillaries in white matter. Anat Rec (Hoboken). 2010 Aug;293(8):1400-7.
99. Li C, Yang S, Chen L, Lu W, Morrison JH, Tang Y*. Stereological methods for estimating the myelin sheaths of the myelinated fibers in white matter. Anat Rec. 2009;292(10):1648-1655.
100. Tang Y, Nyengaard JR*, Andersen JB, Baandrup U, Gundersen HJ. The application of stereological methods for estimating structural parameters in the human heart. Anat Rec. 2009;292(10):1630-1647.
101. Zhang W, Yang S, Li C, Chen L, Tang Y*. Stereological investigation of age-related changes of myelinated fibers in the rat cortex. J Neurosci Res. 2009;87 (13):2872-2880.
102. Zhang J, Yang JQ, He BC, Zhou QX, Yu HR, Tang Y, Liu BZ. Berine and total base from rhizome coptis chinensis attenuate brain injury in an aluminum-induced rat model of neurodegenerative disease. Sandi Med J. 2009;30(6):760-766.
103. Li C, Yang S, Zhang W, Lu W, Nyengaard JR, Morrison JH, Tang Y*. Demyelination induces the decline of the myelinated fiber length in aged white matter. Anat Rec. 2009;292 (4): 528-535.
104. Yang S, Li C, Lu W, Zhang W, Wang WW, Tang Y*. The myelinated fiber changes in the white matter of aged female Long-Evans rats. J Neurosci Res. 2009;7 (7): 1582-1590.
105. Li C, Yang S, Zhang W, Shi XY, Wang WW, Nyengaard JR, Tang Y*. Unbiased stereological quantification of the unmyelinated fibers in rat brain white matter. Neurosci Lett. 2008;437 (1):38-41.
106. Yang S, Li C, Zhang W, Wang WW, Tang Y*. Sex differences in the white matter and myelinated nerve fibers of Long-Evans rats. Brain Res. 2008;1216:16-23.
107. Yang S, Li S, Zhang W, Wang WW, Nyengaard JR, Tang Y*. Application of stereological method to study the white matter and myelinated fibers therein of rat brain. Image Anal Stereol. 2008;27:125-132, 2008.
108. Zhang W, Li C, Yang S, Xu C, Wang WW, Nyengaard JR, Tang Y*. A stereological method for estimating the total length and size of myelin fibers in rat cerebral cortex. J Neurosci Meth. 2008;172 (1):21-26.
109. Ishiyama G, Tokita J, Lopez I, Tang Y, Ishiyama A. Unbiased stereological estimation of the spiral ligament and stria vascularis volumes in aging and Meniere’s disease using archival human temporal bones. J Assoc Res Otolaryngol. 2007;8:8-17.
110. Guo FJ*, Song FZ, Zhang J, Li J, Tang Y. Study of transcription activity of X—box binding protein 1 gene in human different cell lines. J Genet Genomics. 2007;34(9):790-799.
111. Ishiyama G, Finn M, Lopez I, Tang Y, Baloh RW, Ishiyama A. Unbiased quantification of Scarpa’s ganglion neurons in aminoglycoside ototoxicity. J Vestibul Res. 2005;15:197-202.
112. Lopez I, Ishiyama G, Tang Y, Tokita J, Baloh RW, Ishiyama A. Regional estimates of hair cells and supporting cells in the human crista ampullaris. J Neurosci Res. 2005;2:421-431.
113. Lopez I, Ishiyama G, Tang Y, Frank M, Baloh RW, Ishiyama A. Estimation of the number of nerve fibers in the human vestibular endorgans using unbiased stereology and immunohistochemistry. J Neurosci Meth. 2005;145:37-46.
114. Tang Y, Pakkenberg B, Nyengaard JR*. Myelinated nerve fibers in the subcortical white matter of cerebral hemispheres are preserved in alcoholic subjects. Brain Res. 2004;1029 (2):162-167.
115. Ishiyama A, Lopez I, Ishiyama G, Tang Y. Unbiased quantification of the microdissected human Scarpa’s ganglion neurons. Laryngoscope. 2004;14 (8):1496-1499.
116. Wulfsohn D, Nyengaard JR*, Tang Y. Postnatal growth of cardiomyocytes in the left ventricle of the rat. Anat Rec. 2004;277: 236-247.
117. Tang Y, Janssen WGM, Hao J, Roberts J, Mckay H, Lasley B, Allen PB, Greengard P, Rapp PR, Kordower JH, Hof PR, Morrison JH*. Estrogen replacement increases spinophilin-immunoreactive spine number in the prefrontal cortex of female rhesus monkeys. Cereb Cortex. 2004;14: 215-223.
118. Hao J, Janssen WGM, Tang Y, Roberts J, Mckay H, Lasley B, Allen PB, Greengard P, Rapp PR, Kordower JH, Hof PR, Morrison JH*. Estrogen increases number of spinophilin-immunoreactive spines in the hippocampus of young and aged female rhesus monkeys. J Comp Neurol. 2003;465:540-550.
119. Marner L, Nyengaard JR, Tang Y, Pakkenberg B*. Marked loss of myelinated fiber in the human brain with age. J Comp Neurol. 2003;462:144-152.
120. Tang Y, Nyengaard JR*, Pakkenberg B, Gundersen HJ. Stereology of neuronal conncections (myelinated fibers of white matter and synapses of neocortex) in human brain. Image Analysis & Stereology. 2003;22:171-182.
121. Tang Y, Lopez I, Ishiyama A*. Apllication of unbiased stereology on archival human temporal bone. Laryngoscope. 2002;112(3):526-533.
122. Tang Y, Lopez I, Baloh, RW*. Age-related change of the neuronal number in the human medial vestibular nucleus: a stereological investigation. J Vestibul Res.2002;11 (6): 357-363.
123. Whitman GT, Tang Y, Lin A, Baloh RW*. A prospective study of cerebral white matter abnormalities in older people with gait dysfunction. Neurology. 2001;57: 990-994.
124. Tang Y, Nyengaard JR*, De Groot DMG, Gundersen HJG. Total regional and global number of synapses in the human brain neocortex. Synapse.2001;41: 258-273.
125. Park JJ, Tang Y, Lopez I, Ishiyama A. Unbiased estimation of human vestibular ganglion neurons. Ann N Y Acad Sci. 2001 Oct:942:475-8.
126. Tang Y, Whitman GT, Lopez I, Baloh RW*. Brain volume changes on longitudinal magnetic resonance imaging in normal older people. J Neuroimaging. 2001 Oct;11(4):393-400.
127. Park JJ, Tang Y, Lopez I, Ishiyama A*. Age-related change in the number of neurons in the human vestibular ganglion. J Comp Neurol. 2001;431:437-443.
128. Ishiyama A, Agena J, Lopez I, Tang Y. Unbiased stereological quantification of neurons in the human spiral ganglion. Neurosci Lett. 2001;304:93-96.
129. Park JJ, Tang Y, Lopez I, Ishiyama A. Unbiased stereological quantification of neurons on the human vestibular ganglion. NeuroReport. 2000;11(4): 853-857.
130. Whitman GT, Tang Y, Lin A, Baloh RW. Natural history of cerebral hemispheric white matter MRI hyperintensities in older people. Neurology. 2000;54 (Suppl 3): A 219.
131. Tang Y, Whitman GT, Lopez I, Baloh RW*. Brain volume changes on longitudinal MRIs in normal older people. Neurology. 2000;54 (Suppl 3): A 107.
132. Tang Y, Nyengaard JR, Baandrup U, Gundersen HJG*. Design-based stereology of human heart.Acta Stereologica. 1999;18(3):367-380.
133. Tang Y, Ph.D. Dissertation"A stereological study of neuronal connections(myelinated fibers of white matter and synapses of neocortex)in the human brain. Dan Med Bull, 46(1):374, 1999. 18
134. Tang Y*, Nyengaard JR, Pakkenberg B, Gundersen HJG. Age-induced white matter changes in the human brain: A stereological investigation. Neurobiol Aging. 1997;18(6): 609-615.
135. Tang Y, Nyengaard JR*. A stereological method for estimating the total length and size of myelin fibers in human brain white matter. J Neurosci Meth. 1997;73: 193-200.
