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刘太行
副研究员,硕士生导师
招生专业:生物信息学
研究方向:生物信息学
通讯地址:重庆市渝中区医学院路1号重庆医科大学崇医楼516房间
电子邮箱(电话):liuth@cqmu.edu.cn

个人简介

刘太行2017年加入重庆医科大学,就职于基础医学院生物信息教研室,副研究员、硕士生导师、理学博士,主要从事生殖生物学领域胎盘源性疾病研究。主持国家自然科学基金青年项目,中国博士后科学基金面上项目及省部级科研项目2项。以第一/通讯作者在LancetCell Death DiscovMol Hum ReprodFEBS J等发表SCI论文20余篇。作为大学生创新创业指导教师,先后获得5项国家级一二等奖(含特别奖),3项国家级三等奖及十余项省部级奖项。

教育背景及工作经历

2008-2012 河南农业大学,生物工程专业,学士

2012-2017 西南大学,细胞生物学专业,硕博连读

2017-2019  重庆医科大学大学,基础医学博士后流动站,师资博士后

2019-2020  重庆医科大学大学,基础医学学院,生物信息教研室,讲师

2020-至今 重庆医科大学大学,基础医学学院,生物信息教研室,副研究员

主持科研项目

2019年,国家自然科学基金青年科学基金项目,21万元(No.81801458

2019年,全职博士后和出站留(来)渝博士后资助,15万元

2018年,重庆市博士后科研项目特别资助,10万元(No.XmT2018022

2017年,第63批中国博士后科学基金面上资助,5万元(No. 2018M633328

代表性论文、专利

(1) Cai Q.Y. #, Deng B.N., Liu T.H.*. The REVAMP trial: key questions remain. Lancet. 2024. DOI: 10.1016/S0140-673623)01920-7.

(2) Li X.#, Cai Q.Y.#, Luo X., Wang Y.H., Shao L.Z., Luo S.J., Wang L., Wang Y.X., Lan X.*, Liu T.H.*. Gestational diabetes mellitus aggravates adverse perinatal outcomes in women with intrahepatic cholestasis of pregnancy. Diabetol Metab Syndr. 2024. DOI: 10.1186/s13098-024-01294-z.

(3) Li X.#, Li Z.H., Wang Y.X.*, Liu T.H.*. A comprehensive review of human trophoblast fusion models: recent developments and challenges. Cell Death Discov. 2023. DOI: 10.1038/s41420-023-01670-0.

(4) Cai Q.Y.#, Li X. #, Yang Y., Luo X., Luo S.J., Xiong J., He Z.Y., Chen Y., Mou Y.W., Hu J.Y., Yang S., Lan X.*, Liu T.H.*. Rational use of drugs to alleviate adverse outcomes caused by COVID-19 quarantine in women with intrahepatic cholestasis of pregnancy. Front Med Lausanne). 2023. DOI: 10.3389/fmed.2023.1122873.

(5) Wu Z.H.#, Li F.F., Ruan L.L., Feng Q., Zhang S., Li Z.H., Otoo A., Tang J., Fu L.J.*, Liu T.H.*, Ding Y.B.*. miR-181d-5p, which is upregulated in fetal growth restriction placentas, inhibits trophoblast fusion via CREBRF. J Assist Reprod Genet. 2023. DOI: 10.1007/s10815-023-02917-6.

(6) Cai Q.Y.#, Yang Y., Ruan L.L., Wang D.D., Cui H.L., Yang S., Liu W.J., Luo X.*, Liu T.H.*, Effects of COVID-19 home quarantine on pregnancy outcomes of patients with gestational diabetes mellitus: a retrospective cohort study. J Matern Fetal Neonatal Med. 2023. DOI: 10.1080/14767058.2023.2193284.

(7) Li Z.H.#, Li X., Li F.F., Wu Z.H., Xie Y.L., Zhang S., Chen X.M., Wang Y.X.*, Ding Y.B.*, Liu T.H.*, The roles of ADAMDEC1 in trophoblast differentiation during normal pregnancy and preeclampsia. Mol Hum Reprod. 2022. DOI: 10.1093/molehr/gaac014.

(8) Cai Q.Y.#, Yang Y., Wang Y.H., Cui H.L., Wu X.P., Liao K.M., Luo X.*, Liu T.H.*, Home Quarantine: A Double-Edged Sword During COVID-19 Pandemic for Hypertensive Disorders of Pregnancy and the Related Complications. Diabetes Metab Syndr Obes. 2022. DOI: 10.2147/DMSO.S374482

(9) Liu T.H.#, Dong, X.L., Chen P., Zhang Q., Zhou, X.L., Lu, C.*, Pan, M. H.*. Geminin is essential for DNA re-replication in the silk gland cells of silkworms. Experimental Cell Research. 2022. DOI: 10.1016/j.yexcr.2021.112951.

(10) Liu T.H.#, Wei Y., Dong, X L., Chen P., Wang L., Yang, X., Lu, C.*, Pan, M. H.*. The dual roles of three MMPs and TIMP in innate immunity and metamorphosis in the silkworm, Bombyx mori. FEBS Journal. 2022. DOI: 10.1111/febs.16313.

(11) Song H.#, Liu T.H.#, Wang Y.H., Li F.F., Ruan L.L., Adu-Gyamfi E.A., Hu S.C., Chen X.M., Ding Y.B., Fu L.J.*. Appropriate expression of P57kip2 drives trophoblast fusion via cell cycle arrest. Reproduction. 2021. Doi: 10.1530/REP-20-0638.

(12) Adu-Gyamfi E.A.#, Lamptey. J., Chen X.M., Li F.F., Li C., Ruan L.L., Yang X.N., Liu T.H.*, Wang, Y.X.* Ding Y.B.*. Iodothyronine deiodinase 2 DiO2) regulates trophoblast cell line cycle, invasion and apoptosis; and its downregulation is associated with early recurrent miscarriage. Placenta. 2021. DOI: 10.1016/j.placenta.2021.06.004.

(13) Duan F.M.#, Fu L.J.#, Wang Y.H., Adu-Gyamfi E.A., Ruan L.L., Xu Z.W., Xiao S.Q., Chen X.M., Wang Y.X., Liu T.H.*, Ding Y.B.*. THBS1 regulates trophoblast fusion through a CD36-dependent inhibition of cAMP, and its upregulation participates in preeclampsia. Genes and Diseases. 2020. DOI: 10.1016/j.gendis.2020.05.007.

(14) Xu B.R.#, Chen X.Y., Ding Y.B., Chen C., Liu T.H.*, Zhang H.*, Abnormal angiogenesis of placenta in progranulin‑deficient mice, Molecular Medicine Reports, 2020. DOI: 10.3892/mmr.2020.11438.